Description

Cyclopropanecarboxylic Acid, 2-Fluoro-2-(1-Methylethenyl)-, Methyl Ester is a high-value, fluorinated cyclopropane derivative, a key building block in advanced organic synthesis. This compound matters for its unique structural motif, combining a reactive alkene and a fluorine atom on a strained cyclopropane ring, enabling precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and insecticides, where the fluorinated cyclopropane structure enhances biological activity and environmental stability.
• Advanced Material Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with tailored thermal and chemical resistance properties.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands and organometallic catalysts for asymmetric synthesis, leveraging its defined three-dimensional geometry.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the stereoelectronic effects of fluorine in small, strained ring systems.
• Chemical Biology Probes: Utilized to synthesize molecular probes for investigating enzyme mechanisms and protein-ligand interactions due to its bioisosteric potential.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Fluoro-2-(1-Methylethenyl)-, Methyl Ester
CAS No.	760179-39-3
Molecular Formula	C8H11FO2
Molecular Weight	158.17 g/mol
Synonyms	2-Fluoro-2-(1-methylethenyl)cyclopropanecarboxylic acid methyl ester; Methyl 2-fluoro-2-(prop-1-en-2-yl)cyclopropane-1-carboxylate; 2-Fluoro-2-isopropenylcyclopropanecarboxylic acid methyl ester; 2-Fluoro-2-(prop-1-en-2-yl)cyclopropanecarboxylic acid methyl ester; 2-Fluoro-2-vinylcyclopropanecarboxylic acid methyl ester (tautomer); Fluorinated cyclopropane ester; Isopropenyl-fluorocyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Fluoro-2-(1-Methylethenyl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance (REACH, TSCA) ensures a reliable supply for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.