Description

1-Adamantan-1-Yl-4,4,4-Trifluoro-Butane-1,3-Dione is a high-value, fluorinated diketone derivative featuring the rigid adamantane scaffold. This compound is prized for its unique structural properties, which combine the thermal and chemical stability of adamantane with the distinctive electronic characteristics imparted by the trifluoromethyl group. It serves as a critical advanced intermediate for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and materials science, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the stability of the adamantane moiety.
• Ligand & Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and organometallic chemistry.
• Advanced Material Research: Investigated as a monomer or additive for high-performance polymers, coatings, and fluorinated materials requiring enhanced thermal and chemical resistance.
• Organic Synthesis Reagent: Employed in complex organic transformations, including cyclization and fluorination reactions, to introduce the adamantyl-trifluoromethyl motif.

Basic Information

Product Name	1-Adamantan-1-Yl-4,4,4-Trifluoro-Butane-1,3-Dione
CAS No.	758709-48-7
Molecular Formula	C₁₄H₁₇F₃O₂
Molecular Weight	274.28 g/mol
Synonyms	1-Adamantyl-4,4,4-trifluorobutane-1,3-dione; 4,4,4-Trifluoro-1-(1-adamantyl)-1,3-butanedione; 1-(Adamantan-1-yl)-4,4,4-trifluorobutane-1,3-dione; Adamantyl Trifluoromethyl Diketone; ATFD; 1-Adamantyltrifluoroacetylacetone; 1-(1-Adamantyl)-4,4,4-trifluoro-1,3-butanedione
EINECS	Contact for details

Quality Control

Our 1-Adamantan-1-Yl-4,4,4-Trifluoro-Butane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.