Description

Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino-, methyl ester (9Ci) is a highly strained, cage-like bicyclic compound that serves as a valuable and versatile building block in advanced organic synthesis. Its unique three-dimensional structure and bifunctional nature (amine and ester) make it a critical intermediate for constructing complex molecular architectures with enhanced physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, drug discovery, and the development of novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of bioisosteres to improve drug potency, metabolic stability, and selectivity.
• Medicinal Chemistry & Drug Discovery: Used to introduce the rigid, three-dimensional bicyclo[1.1.1]pentane scaffold into lead compounds, a strategy to optimize pharmacokinetic properties and reduce aromatic ring count.
• Agrochemical Synthesis: Intermediate in the research and production of advanced pesticides and herbicides, where its unique structure can contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing novel polymers, ligands, and functional materials with tailored mechanical or electronic properties.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tools for studying biological systems and enzyme mechanisms.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic synthesis and catalysis, exploring new reactions involving strained systems.

Basic Information

Product Name	Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino-, methyl ester (9Ci)
CAS No.	758684-88-7
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid methyl ester; Methyl 3-aminobicyclo[1.1.1]pentane-1-carboxylate; 1-(Methoxycarbonyl)bicyclo[1.1.1]pentane-3-amine; BCP-amine ester; 3-Amino-BCP-methyl ester; 1-Carbomethoxy-3-aminobicyclo[1.1.1]pentane
EINECS	Contact for details

Quality Control

Our Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino-, methyl ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring documentation for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage or after opening to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.