Description

Cyclopropane, 2-(1,1-Dimethylpropoxy)-1,1-Difluoro- (9Ci) is a specialized fluorinated cyclopropane derivative, a high-value intermediate prized for its unique structural motif and reactivity. Its core value lies in enabling the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research where the introduction of fluorine atoms and strained ring systems is critical for modulating biological activity and physicochemical properties. This compound is essential for R&D chemists and process development scientists in the life sciences sector, serving as a key building block for novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorocyclopropane moiety can enhance metabolic stability and bioavailability.
• Material Science Research: Investigated as a precursor for specialty polymers and advanced materials with unique thermal or surface properties.
• Fluorination Chemistry: Serves as a versatile reagent or building block in methodologies for introducing fluorinated cyclopropane groups into target molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Cyclopropane, 2-(1,1-Dimethylpropoxy)-1,1-Difluoro- (9Ci)
CAS No.	757203-91-1
Molecular Formula	C8H14F2O
Molecular Weight	164.19 g/mol
Synonyms	2-(1,1-Dimethylpropoxy)-1,1-difluorocyclopropane; 1,1-Difluoro-2-(1,1-dimethylpropoxy)cyclopropane; 1,1-Difluoro-2-(2-methylbutan-2-yloxy)cyclopropane; 2-(tert-Pentyloxy)-1,1-difluorocyclopropane; tert-Pentyl 1,1-difluorocycloprop-2-yl ether; (1,1-Difluorocycloprop-2-yl)oxy-2-methylbutane
EINECS	Contact for details

Quality Control

Every batch of Cyclopropane, 2-(1,1-Dimethylpropoxy)-1,1-Difluoro- (9Ci) is produced and tested under strict quality management systems to ensure consistency and purity for research and development applications. Our products undergo rigorous analytical characterization, including NMR, GC-MS, and HPLC, to verify identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed and upright to prevent leakage and concentration of vapors. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 94.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.