Description

2,2-Difluoro-2-(Fluorosulfonyl)Acetic Acid Triethylsilyl Ester is a specialized organofluorine and organosilicon building block, valued for its unique bifunctional reactivity. This compound is essential for introducing the difluoro(fluorosulfonyl)acetate moiety into complex molecules, enabling advanced synthetic transformations. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where fluorination can improve activity and environmental profile.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with specific surface properties.
• Electrolyte Additive Research: Investigated for use in next-generation lithium-ion or lithium-sulfur battery electrolytes to improve stability and performance.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex molecules via reactions involving its electrophilic fluorine and silyl ester groups.
• Fluorinated Surfactant/Coating Agent: Potential intermediate for creating fluorosurfactants or surface-modifying agents that impart oil- and water-repellency.

Basic Information

Product Name	2,2-Difluoro-2-(Fluorosulfonyl)Acetic Acid Triethylsilyl Ester
CAS No.	757203-27-3
Molecular Formula	C8H15F3O4SSi
Molecular Weight	292.35 g/mol
Synonyms	Triethylsilyl 2,2-Difluoro-2-(fluorosulfonyl)acetate; (Triethylsilyl) 2,2-Difluoro-2-(fluorosulfonyl)acetate; 2,2-Difluoro-2-(fluorosulfonyl)acetic Acid Triethylsilyl Ester; Acetic Acid, 2,2-Difluoro-2-(fluorosulfonyl)-, Triethylsilyl Ester; TES-DFFA; Triethylsilyl Difluoro(fluorosulfonyl)acetate
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-(Fluorosulfonyl)Acetic Acid Triethylsilyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and process development. We provide comprehensive analytical data, including NMR (¹H, ¹⁹F, ¹³C) and chromatographic purity profiles. Certificates of Analysis (COA) detailing identity, purity, and impurity levels are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile and strong acid/organic solvent nature, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents. Use appropriate explosion-proof equipment. Containers should be kept tightly sealed when not in use to prevent moisture ingress and evaporation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.