Description

1-[(4-tert-Butylphenyl)Sulfonyl]Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific sulfonyl piperidine carboxylic acid structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes, biomarkers, or conjugated molecules for diagnostic and research applications due to its reactive carboxylic acid group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Item	Details
Product Name	1-[(4-tert-Butylphenyl)Sulfonyl]Piperidine-4-Carboxylic Acid
CAS No.	757192-86-2
Molecular Formula	C16H23NO4S
Molecular Weight	325.42 g/mol
Synonyms	4-[(4-tert-Butylphenyl)sulfonyl]piperidine-4-carboxylic acid; 1-(4-tert-Butylbenzenesulfonyl)piperidine-4-carboxylic acid; 4-Carboxy-1-(4-tert-butylphenylsulfonyl)piperidine; Piperidine-4-carboxylic acid, 1-[(4-(1,1-dimethylethyl)phenyl)sulfonyl]-; 757192-86-2; tert-Butylphenyl sulfonyl piperidine carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[(4-tert-Butylphenyl)Sulfonyl]Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.