Description

Cyclobutanemethanamine, 3-Amino-2,2-Dimethyl-, cis- (9Ci) is a specialized chiral amine building block featuring a constrained cyclobutane ring system. This compound matters as a high-value intermediate for the synthesis of complex molecules, offering unique stereochemistry and structural rigidity to influence the biological activity and pharmacokinetic properties of final products. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the cis-dimethyl-substituted cyclobutane structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require rigid, aliphatic amine components.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tool compounds to study biological pathways and protein interactions.

Basic Information

Product Name	Cyclobutanemethanamine, 3-Amino-2,2-Dimethyl-, cis- (9Ci)
CAS No.	757139-71-2
Molecular Formula	C7H15N
Molecular Weight	113.20 g/mol
Synonyms	cis-3-Amino-2,2-dimethylcyclobutanemethanamine; (1s,3s)-3-Amino-2,2-dimethylcyclobutanemethanamine; 2,2-Dimethyl-3-aminocyclobutanemethanamine (cis); 3-Amino-2,2-dimethylcyclobutanemethylamine; cis-1-Aminomethyl-2,2-dimethyl-3-aminocyclobutane; Bicyclo[2.1.1]hexan-6-ylmethanamine, 1-amino- (related structure); Chiral Cyclobutane Diamine Derivative
EINECS	Contact for details

Quality Control

Our Cyclobutanemethanamine, 3-Amino-2,2-Dimethyl-, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.