Description

Cyclopropanecarboxylic Acid, 1-Amino-2-(4-Hydroxyphenyl)- (9Ci) is a specialized chiral compound featuring a cyclopropane ring, an amino group, and a phenolic hydroxyl group, making it a versatile building block for advanced synthesis. This compound is valued for its unique three-dimensional structure, which is critical for modulating the biological activity and physicochemical properties of target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

This advanced intermediate serves as a key chiral synthon in several high-value research and development applications:

• Pharmaceutical Intermediate: Core building block for the synthesis of potential drug candidates, particularly in oncology, CNS disorders, and metabolic disease research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the cyclopropane moiety enhances stability and bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis to create enantiomerically pure compounds.
• Peptidomimetics and Bioisosteres: The rigid cyclopropane scaffold is employed to replace peptide bonds or other motifs in the design of metabolically stable therapeutic peptides.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-(4-Hydroxyphenyl)- (9Ci)
CAS No.	756765-09-0
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	1-Amino-2-(4-hydroxyphenyl)cyclopropanecarboxylic acid; (1-Amino-2-(4-hydroxyphenyl)cyclopropyl)methanoic acid; 2-(4-Hydroxyphenyl)-1-aminocyclopropanecarboxylic acid; 1-Amino-2-(4-hydroxyphenyl)cyclopropane-1-carboxylic acid; 4-Hydroxy-α-(aminomethyl)benzenepropanoic acid, γ-lactone (related forms); AHPCPA (abbreviation).
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 1-Amino-2-(4-Hydroxyphenyl)- (9Ci) adheres to stringent quality protocols suitable for research and development use. Each batch is analytically verified using techniques such as HPLC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.