Description

1-Piperidineethanesulfonamide, n-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a high-value, multi-functional organic building block that integrates a piperidine-sulfonamide moiety with a boronic ester pinacol group. This compound matters for its critical role in modern synthetic chemistry, particularly in facilitating Suzuki-Miyaura cross-coupling reactions, which are foundational for constructing complex molecules. It is primarily needed by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the boronic ester for efficient carbon-carbon bond formation.
• Material Science: Serves as a precursor for functional polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in activity-based protein profiling (ABPP) and bioconjugation strategies.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and catalysis research within university and CRO laboratories.
• Scale-up & Process Chemistry: Supports route scouting and optimization for the commercial-scale production of fine chemicals.

Basic Information

Product Name	1-Piperidineethanesulfonamide, n-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	756520-97-5
Molecular Formula	C19H31BN2O4S
Molecular Weight	394.34 g/mol
Synonyms	N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1-piperidineethanesulfonamide; 3-(1-Piperidineethanesulfonamido)phenylboronic acid pinacol ester; 2-(Piperidin-1-yl)ethanesulfonamide, N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 756520-97-5; B-3-[[(2-Piperidinoethyl)sulfonyl]amino]phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Piperidineethanesulfonamide derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up activities with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.