Description

1-Morpholino-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenoxy)propan-2-ol is a sophisticated bifunctional organic building block that combines a morpholine moiety with a protected boronic acid ester. This compound is valued for its dual functionality, enabling its use as a key intermediate in complex multi-step syntheses, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable boronic ester reagent for palladium-catalyzed carbon-carbon bond formation to create biaryl structures.
• Ligand and Catalyst Development: Used in the preparation of novel ligands and organocatalysts due to the coordinating properties of the morpholine nitrogen.
• Polymer and Material Science: Incorporated into specialty monomers for creating functional polymers with tailored properties.
• Agrochemical Research: Employed in the discovery and synthesis of new crop protection agents and herbicides.
• Chemical Biology Probes: Utilized for synthesizing molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	1-Morpholino-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenoxy)propan-2-ol
CAS No.	756520-73-7
Molecular Formula	C19H30BNO5
Molecular Weight	363.26 g/mol
Synonyms	2-Morpholino-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-2-propanol; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)-3-morpholinopropan-2-ol; 2-Propanol, 1-morpholino-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-; PINACOL (4-(3-MORPHOLINO-2-HYDROXYPROPOXY)PHENYL)BORONATE
EINECS	Contact for details

Quality Control

Our 1-Morpholino-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenoxy)propan-2-ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.