Description

4-(1,1-Dioxido-2-Isothiazolidinyl)Phenylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound is valued for its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl-boronate functionalities.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of chemical probes and bioconjugation reagents for studying biological processes.
• Catalyst Ligand Development: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-(1,1-Dioxido-2-Isothiazolidinyl)Phenylboronic Acid Pinacol Ester
CAS No.	756520-72-6
Molecular Formula	C15H20BNO4S
Molecular Weight	321.20 g/mol
Synonyms	4-(1,1-Dioxido-2-isothiazolidinyl)benzeneboronic acid pinacol ester; 4-(1,1-Dioxido-1,2-thiazolidin-2-yl)phenylboronic acid pinacol ester; 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,2-thiazolidine 1,1-dioxide; 4-(1,1-Dioxido-2-isothiazolidinyl)phenylboronic acid, pinacol ester; B-[4-(1,1-Dioxido-2-isothiazolidinyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-(1,1-Dioxido-2-Isothiazolidinyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.