Description

2-Amino-3-Benzyloxypyridine-5-Boronic Acid Pinacol Ester is a high-value, multifunctional boronic ester derivative crucial for modern synthetic chemistry. Its core value lies in enabling efficient, selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or cross-linking agent in the creation of organic electronic materials, such as polymers for OLEDs or sensors.
• Chemical Biology: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways and target engagement.
• Catalyst Ligand Precursor: Can be utilized to synthesize novel ligand systems for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Amino-3-Benzyloxypyridine-5-Boronic Acid Pinacol Ester
CAS No.	756520-57-7
Molecular Formula	C18H23BN2O3
Molecular Weight	326.20 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(benzyloxy)pyridin-2-amine; 2-Amino-3-benzyloxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Benzyloxy-2-amino-5-pyridineboronic acid pinacol ester; 2-Amino-3-(phenylmethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; B-(2-Amino-3-benzyloxy-5-pyridinyl)boronic acid pinacol ester; AMBZP-BPin
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Benzyloxypyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for critical cross-coupling applications. Certificates of Analysis (COA) with full characterization data are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.