Description

Aziridine, 2-Methyl-1-(1-Methylethyl)-3-Phenyl-, (2S,3R)- (9Ci) is a high-purity, stereochemically defined aziridine derivative, a versatile and reactive three-membered heterocyclic building block. Its chiral structure makes it a critical intermediate for the synthesis of complex molecules where precise stereochemistry is essential for biological activity or material properties. This compound is primarily needed by pharmaceutical R&D and advanced material science laboratories for developing novel active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel APIs, particularly in oncology and central nervous system (CNS) drug discovery.
• Asymmetric Synthesis: Used as a building block for constructing complex natural products and chiral auxiliaries due to its defined (2S,3R) configuration.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for the synthesis of specialty polymers with tailored properties.
• Agrochemical Research: Intermediate in the synthesis of advanced, stereospecific crop protection agents and herbicides.
• Ligand & Catalyst Development: Precursor for creating novel chiral ligands used in asymmetric catalysis for fine chemical manufacturing.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and new reaction development.

Basic Information

Product Name	Aziridine, 2-Methyl-1-(1-Methylethyl)-3-Phenyl-, (2S,3R)- (9Ci)
CAS No.	756411-90-2
Molecular Formula	C13H17N
Molecular Weight	187.28 g/mol
Synonyms	(2S,3R)-2-Methyl-1-isopropyl-3-phenylaziridine; (2S,3R)-1-Isopropyl-2-methyl-3-phenylaziridine; 2-Methyl-1-(1-methylethyl)-3-phenylaziridine, (2S,3R)-; (2S,3R)-1-(Propan-2-yl)-2-methyl-3-phenylaziridine; trans-1-Isopropyl-2-methyl-3-phenylaziridine; Chiral phenylaziridine derivative; Aziridine, 1-isopropyl-2-methyl-3-phenyl-, (2S,3R)-
EINECS	Contact for details

Quality Control

Our high-purity chiral aziridine is manufactured under strict quality protocols. Every batch undergoes comprehensive analytical testing, including chiral HPLC to confirm enantiomeric excess and standard spectroscopic methods for identity and purity verification. Certificates of Analysis (COA) detailing assay, chiral purity, and impurity profiles are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.