Description

2-Methoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is a high-value organoboron building block, specifically a pinacol boronic ester derivative of a substituted benzonitrile. This compound is critical for enabling advanced cross-coupling reactions, such as the Suzuki-Miyaura coupling, which are foundational to modern synthetic chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring aryl-aryl bond formation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate complex aromatic systems.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as polymers for OLEDs or organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and bioconjugates for diagnostic and research applications.
• Academic & Industrial R&D: Essential for methodological development and scale-up studies in synthetic organic chemistry laboratories worldwide.
• Liquid Crystal & Advanced Polymer Synthesis: Used to introduce functionalized aromatic units into polymers and liquid crystal molecules to tailor their properties.

Basic Information

Product Name	2-Methoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile
CAS No.	755030-94-5
Molecular Formula	C14H18BNO3
Molecular Weight	259.11 g/mol
Synonyms	4-Cyano-3-methoxyphenylboronic acid pinacol ester; 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxybenzonitrile; 2-Methoxy-4-(pinacolatoboron)benzonitrile; 4-Cyano-3-methoxybenzeneboronic acid pinacol ester; PINACOL 2-METHOXY-4-CYANOPHENYLBORONATE; (4-Cyano-3-methoxyphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture ingress, which may affect stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.