Description

2-(3-Methoxy-4-Nitrophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality precursors for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Industrial R&D: A fundamental reagent for method development and scale-up in synthetic chemistry laboratories worldwide.
• Ligand & Catalyst Preparation: Can be utilized in the synthesis of specialized ligands and organometallic catalysts.

Basic Information

Item	Information
Product Name	2-(3-Methoxy-4-Nitrophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	755026-96-1
Molecular Formula	C₁₃H₁₈BNO₅
Molecular Weight	279.10 g/mol
Synonyms	3-Methoxy-4-nitrophenylboronic acid pinacol ester; (3-Methoxy-4-nitrophenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(3-methoxy-4-nitrophenyl)-1,3,2-dioxaborolane; Pinacol (3-Methoxy-4-nitrophenyl)boronate; 2-(3-Methoxy-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 755026-96-1; Boronic acid, B-(3-methoxy-4-nitrophenyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of our 2-(3-Methoxy-4-Nitrophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to support cGMP and ISO standards, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.