Description

Cyclobutanemethanol, 2,2-Dimethyl-3-(1-Methylethylidene)-, (1S)- (9Ci) is a high-purity, chiral cyclobutane derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block, offering a unique, strained ring structure and defined stereochemistry for constructing complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the cyclobutane core imparts specific biological activity.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Asymmetric Catalysis Ligand Scaffold: The defined stereocenter and rigid structure make it a candidate for developing novel chiral ligands and organocatalysts.
• Fragrance & Flavor Chemistry: Potential use in synthesizing novel odorants and flavor compounds that leverage its unique hydrocarbon skeleton.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions.

Basic Information

Product Name	Cyclobutanemethanol, 2,2-Dimethyl-3-(1-Methylethylidene)-, (1S)- (9Ci)
CAS No.	754227-25-3
Molecular Formula	C10H18O
Molecular Weight	154.25 g/mol
Synonyms	(1S)-2,2-Dimethyl-3-(1-methylethylidene)cyclobutanemethanol; (1S)-3-Isopropylidene-2,2-dimethylcyclobutanemethanol; (S)-2,2-Dimethyl-3-(prop-1-en-2-yl)cyclobutan-1-yl)methanol; (1S)-3-(2-Methylprop-1-en-1-yl)-2,2-dimethylcyclobutanemethanol; Light-sensitive (store away from light)
EINECS	Contact for details

Quality Control

Our Cyclobutanemethanol, 2,2-Dimethyl-3-(1-Methylethylidene)-, (1S)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.