Description

4-Benzyloxyphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound matters as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecules with high selectivity. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional organic compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aryl halides and this protected boronate ester.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly those containing biphenyl or substituted phenyl motifs.
• Agrochemical Development: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced properties.
• Material Science & OLED Research: Employed in the synthesis of organic semiconductors, light-emitting materials, and advanced polymers.
• Ligand & Catalyst Preparation: Useful for constructing sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of molecular probes.

Basic Information

Product Name	4-Benzyloxyphenylboronic Acid, Pinacol Ester
CAS No.	754226-40-9
Molecular Formula	C19H23BO3
Molecular Weight	310.20 g/mol
Synonyms	4-(Benzyloxy)phenylboronic acid pinacol ester; 2-[4-(Phenylmethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(Benzyloxy)benzeneboronic acid pinacol ester; 4-Benzyloxybenzeneboronic Acid Pinacol Ester; 4-(Benzyloxy)phenylboronic Acid Neopentyl Glycol Ester (common alternative); B-[4-(Phenylmethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Benzyloxyphenyl-Bpin; 4-BnO-Ph-Bpin
EINECS	Contact for details

Quality Control

Our 4-Benzyloxyphenylboronic Acid, Pinacol Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and production. Each lot undergoes comprehensive analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to confirm identity and purity. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.