Description

7-Azaindole-5-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and a versatile building block for Suzuki-Miyaura cross-coupling reactions. This compound is critical for medicinal chemists and process development scientists engaged in the synthesis of novel heterocyclic compounds, particularly for drug discovery programs targeting kinase inhibition. It is primarily utilized by research institutions and pharmaceutical companies in the development of active pharmaceutical ingredients (APIs) and other complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those containing the 7-azaindole scaffold.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic ester reagent for forming carbon-carbon bonds in the construction of biaryl and heterobiaryl structures.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and lead optimization for developing new therapeutic agents, particularly kinase inhibitors.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical libraries.
• Agrochemical Synthesis: Potential building block for developing new active ingredients in crop protection products.
• Material Science: Can be used in the synthesis of organic electronic materials and functional polymers.

Basic Information

Product Name	7-Azaindole-5-Boronic Acid Pinacol Ester
CAS No.	754214-56-7
Molecular Formula	C13H17BN2O2
Molecular Weight	244.10 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-5-boronic acid, pinacol ester; 5-(Pinacolatoboryl)-7-azaindole; 7-Azaindol-5-ylboronic acid pinacol ester; 5-Borono-7-azaindole pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-azaindole; Azaindole boronic ester
EINECS	Contact for details

Quality Control

Our 7-Azaindole-5-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.