Description

1-Bromo-2-Chloro-4,5-Dimethoxybenzene is a high-purity halogenated dimethoxybenzene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its precise structure offers controlled reactivity, making it essential for constructing complex molecular architectures where regioselective functionalization is required. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring specific halogen and methoxy substitution patterns.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport molecules or monomers for conductive polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological mechanisms due to its derivatizable halogen groups.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CROs/CMOs developing proprietary compounds for clients.

Basic Information

Product Name	1-Bromo-2-Chloro-4,5-Dimethoxybenzene
CAS No.	753502-60-2
Molecular Formula	C8H8BrClO2
Molecular Weight	251.51 g/mol
Synonyms	2-Bromo-1-Chloro-4,5-Dimethoxybenzene; 4,5-Dimethoxy-1-bromo-2-chlorobenzene; 1-Chloro-2-bromo-4,5-dimethoxybenzene; Benzene, 1-bromo-2-chloro-4,5-dimethoxy-; 753502-60-2; 4,5-Dimethoxy-2-chlorobromobenzene; 2-Chloro-4,5-dimethoxybromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-4,5-Dimethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.