Description

4-Isoxazolecarboxylic Acid, 5-Hydroxy-3-Methyl-, Methyl Ester (9Ci) is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoxazole ring's bioactivity.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-catalyzed reactions and organocatalysts.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of novel polymers with specific thermal or optical properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses producing bespoke compounds for client R&D programs.

Basic Information

Product Name	4-Isoxazolecarboxylic Acid, 5-Hydroxy-3-Methyl-, Methyl Ester (9Ci)
CAS No.	753486-91-8
Molecular Formula	C6H7NO4
Molecular Weight	157.12 g/mol
Synonyms	Methyl 5-hydroxy-3-methyl-1,2-oxazole-4-carboxylate; 5-Hydroxy-3-methylisoxazole-4-carboxylic acid methyl ester; 3-Methyl-5-hydroxy-4-isoxazolecarboxylic acid methyl ester; 4-Carbomethoxy-5-hydroxy-3-methylisoxazole; Methyl 3-methyl-5-hydroxyisoxazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Isoxazolecarboxylic Acid, 5-Hydroxy-3-Methyl-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.