Description

1-(Benzo[D][1,3]Dioxol-5-Yl)-2-Bromo-2-(6-Methylpyridin-2-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular architecture combining a benzodioxole and a brominated pyridyl ethanone moiety. This compound matters as a critical building block in modern synthetic organic chemistry, enabling the construction of complex molecules with high precision and yield. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and novel chemical entities (NCEs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Organic Synthesis Building Block: Serves as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Negishi) and other C-C bond-forming transformations.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents and pesticides.
• Academic & Industrial R&D: Employed in methodological development and as a model compound in synthetic chemistry laboratories.

Basic Information

Product Name	1-(Benzo[D][1,3]Dioxol-5-Yl)-2-Bromo-2-(6-Methylpyridin-2-Yl)Ethanone
CAS No.	752260-31-4
Molecular Formula	C₁₅H₁₂BrNO₃
Molecular Weight	334.17 g/mol
Synonyms	2-Bromo-1-(1,3-benzodioxol-5-yl)-2-(6-methyl-2-pyridinyl)ethanone; 1-(1,3-Benzodioxol-5-yl)-2-bromo-2-(6-methylpyridin-2-yl)ethanone; 2-Bromo-2-(6-methylpyridin-2-yl)-1-(benzo[d][1,3]dioxol-5-yl)ethan-1-one; 752260-31-4; Ethanone, 1-(1,3-benzodioxol-5-yl)-2-bromo-2-(6-methyl-2-pyridinyl)-; Bromo(6-methylpyridin-2-yl)(1,3-benzodioxol-5-yl)methanone precursor
EINECS	Contact for details

Quality Control

Our 1-(Benzo[D][1,3]Dioxol-5-Yl)-2-Bromo-2-(6-Methylpyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.