Description

Butanedioic Acid, 2-Bromo-3-Hydroxy-, Dimethyl Ester, (2R,3R)- (9Ci) is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its defined stereochemistry and functional group array make it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in asymmetric synthesis.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Academic & Industrial Research: Serves as a model compound or starting material in methodological studies for new catalytic asymmetric reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Ligand and Catalyst Development: Useful for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.

Basic Information

Product Name	Butanedioic Acid, 2-Bromo-3-Hydroxy-, Dimethyl Ester, (2R,3R)- (9Ci)
CAS No.	749917-66-6
Molecular Formula	C6H9BrO5
Molecular Weight	241.04 g/mol
Synonyms	(2R,3R)-Dimethyl 2-bromo-3-hydroxysuccinate; (2R,3R)-2-Bromo-3-hydroxysuccinic acid dimethyl ester; Dimethyl (2R,3R)-2-bromo-3-hydroxysuccinate; (R,R)-Dimethyl 2-bromo-3-hydroxysuccinate; Succinic acid, 2-bromo-3-hydroxy-, dimethyl ester, (2R,3R)-; 2-Bromo-3-hydroxysuccinic acid dimethyl ester, (2R,3R)-; Bromohydroxysuccinic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our production of (2R,3R)-Dimethyl 2-bromo-3-hydroxysuccinate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.