Description

Benzaldehyde, 2-Ethynyl-4-Fluoro- (9Ci) is a specialized aromatic aldehyde building block featuring both an ethynyl and a fluorine substituent. This unique molecular structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical researchers for constructing novel active ingredients and by material scientists exploring new functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags due to the reactivity of the aldehyde and ethynyl groups for bioconjugation (e.g., click chemistry).
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated and rigid-rod components in electronic display and lighting technologies.
• Academic & Contract Research: A versatile building block for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	Benzaldehyde, 2-Ethynyl-4-Fluoro- (9Ci)
CAS No.	749874-24-6
Molecular Formula	C9H5FO
Molecular Weight	148.14 g/mol
Synonyms	2-Ethynyl-4-fluorobenzaldehyde; 4-Fluoro-2-ethynylbenzaldehyde; 2-Ethynyl-4-fluorobenzenecarboxaldehyde; Benzaldehyde, 4-fluoro-2-ethynyl-; (2-Ethynyl-4-fluorophenyl)methanone (tautomer); 4-Fluoro-2-(ethynyl)benzaldehyde
EINECS	Contact for details

Quality Control

Our Benzaldehyde, 2-Ethynyl-4-Fluoro- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and scale-up activities with reliable data.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.