Description

3,4-Pyrrolidinediol,2-(1-Hydroxyethyl)-,[2R-[2Alpha(S*),3Alpha,4Alpha]]-(9Ci) is a high-purity, stereochemically defined pyrrolidine derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its precise stereochemistry and functionalized diol structure make it invaluable for constructing complex molecular architectures with high enantiomeric purity. This compound is essential for research and development in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), especially in therapeutic areas requiring high stereochemical control.
• Asymmetric Catalysis: Used in the synthesis of chiral ligands and organocatalysts for enantioselective transformations in fine chemical manufacturing.
• Chemical Research: Serves as a versatile building block in medicinal chemistry and process chemistry for exploring new synthetic routes and molecular entities.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, agrochemical intermediates, and advanced materials where specific stereochemistry is required.

Basic Information

Product Name	3,4-Pyrrolidinediol,2-(1-Hydroxyethyl)-,[2R-[2Alpha(S*),3Alpha,4Alpha]]-(9Ci)
CAS No.	749145-39-9
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2R,3R,4R)-2-(1-Hydroxyethyl)-3,4-dihydroxypyrrolidine; (2R,3R,4R)-2-(1-Hydroxyethyl)pyrrolidine-3,4-diol; 2-(1-Hydroxyethyl)-3,4-dihydroxypyrrolidine (stereoisomer); Pyrrolidine-3,4-diol, 2-(1-hydroxyethyl)-, (2R,3R,4R)-; (2R,3R,4R)-2-(α-Hydroxyethyl)-3,4-dihydroxypyrrolidine; Chiral Pyrrolidinediol Derivative
EINECS	Contact for details

Quality Control

Every batch of our 3,4-Pyrrolidinediol derivative is manufactured under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, NMR, and mass spectrometry, to ensure identity, purity, and stereochemical integrity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.