Description

Methyl 3-Amino-4,4,4-Trifluorobutyrate is a high-value fluorinated amino acid ester building block, essential for introducing the trifluoromethyl group into complex molecular architectures. Its primary value lies in enabling the synthesis of novel compounds with enhanced metabolic stability, lipophilicity, and bioavailability. This intermediate is critically needed by pharmaceutical and agrochemical R&D teams for developing new active ingredients, including protease inhibitors and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly protease inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF3 group improves biological activity and environmental persistence.
• Peptidomimetics Research: Serves as a crucial component in creating fluorinated peptide analogs for biochemical and medicinal chemistry studies.
• Material Science: Employed in the development of specialty polymers and advanced materials that require fluorinated moieties for specific properties like chemical resistance.
• Chemical Biology Probes: Utilized to synthesize labeled compounds and probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Methyl 3-Amino-4,4,4-Trifluorobutyrate
CAS No.	748746-28-3
Molecular Formula	C5H8F3NO2
Molecular Weight	171.12 g/mol
Synonyms	3-Amino-4,4,4-trifluorobutanoic acid methyl ester; Methyl 3-amino-4,4,4-trifluorobutanoate; 4,4,4-Trifluoro-3-aminobutanoic acid methyl ester; 3-Amino-4,4,4-trifluorobutyric acid methyl ester; Methyl β-amino-4,4,4-trifluorobutyrate; 748746-28-3; 3-Azanyl-4,4,4-trifluorobutanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-4,4,4-Trifluorobutyrate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and production use. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.