Description

1-Methyl-4-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Piperazine is a high-value, advanced pharmaceutical intermediate featuring a piperazine core linked to a pinacol boronate ester. This compound is essential for modern synthetic chemistry, enabling efficient cross-coupling reactions to construct complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for creating biaryl and heterobiaryl structures prevalent in drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a precursor for novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology: Utilized as a probe or linker in bioconjugation and proteomics research.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for client-specific projects.

Basic Information

Product Name	1-Methyl-4-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Piperazine
CAS No.	747413-18-9
Molecular Formula	C17H27BN2O2
Molecular Weight	302.22 g/mol
Synonyms	1-Methyl-4-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperazine; 3-(4-Methylpiperazin-1-yl)phenylboronic acid pinacol ester; 1-Methyl-4-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]piperazine; 747413-18-9; 1-Methyl-4-(3-(pinacolatoboryl)phenyl)piperazine; 3-(1-Methylpiperazin-4-yl)phenylboronic acid pinacol ester; N-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline piperazine derivative
EINECS	Contact for details

Quality Control

Every batch of 1-Methyl-4-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Piperazine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.