Description

3-Chloro-3',4',5'-Trifluorobenzophenone is a high-purity fluorinated benzophenone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique halogenated structure, which provides a versatile scaffold for constructing complex molecules with tailored properties. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, where the trifluoromethyl and chloro groups enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Organic Synthesis Reagent: Acts as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.

Basic Information

Product Name	3-Chloro-3',4',5'-Trifluorobenzophenone
CAS No.	746651-95-6
Molecular Formula	C14H6ClF3O
Molecular Weight	282.64 g/mol
Synonyms	(3-Chlorophenyl)(3,4,5-trifluorophenyl)methanone; 3-Chloro-3',4',5'-trifluorobenzophenone; 3-Chloro-3,4,5-trifluorobenzophenone; 1-(3-Chlorophenyl)-2-(3,4,5-trifluorophenyl)ethanone (common misnomer); 3-Chloro-α,α,α-trifluorobenzophenone; Benzophenone, 3-chloro-3',4',5'-trifluoro-; 746651-95-6
EINECS	Contact for details

Quality Control

Our 3-Chloro-3',4',5'-Trifluorobenzophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.