Description

2,4'-Dibromo-2',6'-difluoroacetophenone is a specialized halogenated acetophenone derivative, serving as a critical building block in advanced organic synthesis. Its precise molecular architecture makes it an invaluable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and high-performance functional chemicals where specific halogen substitution patterns are required.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry research targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the difluoro and dibromo motifs contribute to biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED devices.
• Cross-Coupling Reactions: Utilized in Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions to introduce complex aryl groups.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating functional materials.

Basic Information

Product Name	2,4'-Dibromo-2',6'-Difluoroacetophenone
CAS No.	746630-35-3
Molecular Formula	C8H4Br2F2O
Molecular Weight	313.92 g/mol
Synonyms	1-(2,6-Difluorophenyl)-2,4-dibromoethanone; 2',6'-Difluoro-2,4-dibromoacetophenone; α,2,4-Tribromo-2',6'-difluoroacetophenone; 2,4-Dibromo-1-(2,6-difluorophenyl)ethan-1-one; 2,4-Dibromo-2',6'-difluoroacetophenone
EINECS	Contact for details

Quality Control

Our 2,4'-Dibromo-2',6'-difluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.