Description

(4-Fluoroquinolin-3-Yl)Boronic Acid is a high-purity boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its value lies in its dual functionality, serving as a versatile building block for the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those containing the quinoline scaffold, for therapeutic areas like oncology and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its ability to form carbon-carbon bonds under mild conditions.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, ligands for catalysts, and advanced polymers.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as a boronic acid coupling partner to introduce the 4-fluoroquinolin-3-yl moiety into target molecules efficiently.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	(4-Fluoroquinolin-3-Yl)Boronic Acid
CAS No.	745784-11-6
Molecular Formula	C9H7BBFNO2
Molecular Weight	204.97 g/mol
Synonyms	(4-Fluoro-3-quinolyl)boronic acid; 3-Borono-4-fluoroquinoline; 4-Fluoroquinoline-3-boronic acid; (4-Fluoro-3-quinolinyl)boronic acid; B-(4-Fluoro-3-quinolinyl)boronic acid; 745784-11-6; Boronic acid, B-(4-fluoro-3-quinolinyl)-
EINECS	Contact for details

Quality Control

Our (4-Fluoroquinolin-3-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.