Description

Cyclohexanecarboxylic Acid, 1-Fluoro-2-Hydroxy-, cis- (9Ci) is a fluorinated hydroxycyclohexanecarboxylic acid derivative, a high-value chiral building block in advanced organic synthesis. This compound is critical for introducing both fluorine and hydroxyl functional groups in a stereochemically defined manner, enabling precise molecular design. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with tailored properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorination on molecular conformation and reactivity.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Item	Detail
Product Name	Cyclohexanecarboxylic Acid, 1-Fluoro-2-Hydroxy-, cis- (9Ci)
CAS No.	742037-03-2
Molecular Formula	C7H11FO3
Molecular Weight	162.16 g/mol
Synonyms	cis-1-Fluoro-2-hydroxycyclohexanecarboxylic acid; (1R,2S)-1-Fluoro-2-hydroxycyclohexane-1-carboxylic acid; (1S,2R)-1-Fluoro-2-hydroxycyclohexane-1-carboxylic acid; 1-Fluoro-2-hydroxy-cyclohexanecarboxylic acid, cis-; Fluorohydroxycyclohexanecarboxylic acid; cis-1-Fluoro-2-hydroxycyclohexanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 1-Fluoro-2-Hydroxy-, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements of research and process development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.