Description

6-Chloro-2-Methoxy-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a protected boronic acid, offering enhanced stability and handling characteristics for critical cross-coupling reactions. This advanced intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds in drug discovery and active ingredient synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of carbon-carbon bonds, enabling the synthesis of biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), especially those containing functionalized pyridine cores.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with complex molecular architectures.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Biology Probes: Utilized for synthesizing tagged molecules and probes for studying biological systems and target engagement.

Basic Information

Product Name	6-Chloro-2-Methoxy-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	741709-68-2
Molecular Formula	C12H17BClNO3
Molecular Weight	269.53 g/mol
Synonyms	6-Chloro-2-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(6-Chloro-2-methoxypyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Boronic acid, 6-chloro-2-methoxypyridine-, 1,3,2-dioxaborolane ester; 6-Chloro-2-methoxy-3-pyridineboronic acid pinacol ester; 6-Chloro-2-methoxypyridine-3-boronic acid pinacol ester; (6-Chloro-2-methoxypyridin-3-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Methoxy-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is light-sensitive and easily oxidized; allow the container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.