Description

2-Cyanopyridine-5-Boronic Acid Pinacol Ester is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially in kinase inhibitor and heterocyclic compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific targeting properties.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex molecular architectures.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to introduce the pyridine-cyanoboronic acid moiety into target molecules.

Basic Information

Product Name	2-Cyanopyridine-5-Boronic Acid Pinacol Ester
CAS No.	741709-63-7
Molecular Formula	C₁₃H₁₅BN₂O₂
Molecular Weight	242.08 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile; 2-Cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Cyano-5-pyridineboronic acid pinacol ester; 5-(Pinacolatoboryl)picolinonitrile; 2-Cyanopyridin-5-ylboronic acid pinacol ester; Picolinonitrile, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Cyanopyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.