Description

2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Ethanol is a high-value, functionalized boronic ester derivative that serves as a critical building block in advanced organic synthesis. Its core value proposition lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, particularly the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require a reliable and pure source of a protected boronic acid moiety for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling, enabling the formation of biaryl and heterobiaryl structures common in modern drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic and phenolic architectures.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating advanced organic electronic materials, where the boronate group allows for precise molecular assembly and tuning of electronic properties.
• Polymer & Resin Modification: The terminal hydroxyl group allows for incorporation into polymer backbones or surface functionalization, creating materials with tailored adhesion, compatibility, or reactivity.
• Organic Synthesis & Medicinal Chemistry Research: A versatile reagent in academic and industrial R&D labs for constructing complex molecular libraries and exploring new chemical spaces.
• Sensor Development: Potential use in the synthesis of molecular probes and sensors that leverage the specific reactivity of the boronate ester group.

Basic Information

Product Name	2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Ethanol
CAS No.	741699-47-8
Molecular Formula	C14H21BO4
Molecular Weight	264.12 g/mol
Synonyms	2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]ethan-1-ol; 4-(2-Hydroxyethoxy)phenylboronic acid pinacol ester; 2-[p-(Pinacolboryl)phenoxy]ethanol; 4-(2-Hydroxyethoxy)benzeneboronic acid pinacol ester; 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethanol; Pinacol [4-(2-hydroxyethoxy)phenyl]boronate; [4-(2-Hydroxyethoxy)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Ethanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.