Description

2-Hydroxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is a high-value, multifunctional organic building block that combines a carboxylic acid group with a protected boronic acid moiety. This compound is essential for facilitating complex coupling reactions in advanced organic synthesis, particularly in the pharmaceutical and materials science sectors. It is primarily sought after by research chemists and process development scientists for the construction of novel drug candidates and functional organic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key precursor for constructing biaryl and heterobiaryl structures, which are core scaffolds in many pharmaceuticals and agrochemicals.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Material Science Research: Serves as a monomer or functionalizing agent in the synthesis of organic electronic materials, such as polymers for OLEDs or sensors.
• Ligand Synthesis: Employed to create novel bidentate or tridentate ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes due to its versatile reactivity.
• Agrochemical Development: Acts as an intermediate in the synthesis of new herbicides and fungicides with improved efficacy.

Basic Information

Product Name	2-Hydroxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid
CAS No.	741698-75-9
Molecular Formula	C₁₃H₁₇BO₅
Molecular Weight	264.09 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)salicylic acid; 2-Hydroxy-4-(pinacolatoboryl)benzoic acid; 4-Pinacolatoborylsalicylic Acid; 4-BPin-Salicylic Acid; Salicylic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(Pinacolboranyl)salicylic Acid; 4-(Pinacolatoboron)salicylic Acid; 4-Borono-2-hydroxybenzoic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-Hydroxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.