Description

5-(Trifluoromethyl)-1-Benzofuran is a high-value fluorinated benzofuran derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethyl group, which is essential for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas like oncology, CNS disorders, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF3 group enhances lipophilicity and metabolic stability.
• Material Science Research: Acts as a precursor for functional materials, such as organic semiconductors, liquid crystals, and specialty polymers.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library production.

Basic Information

Product Name	5-(Trifluoromethyl)-1-Benzofuran
CAS No.	741290-20-0
Molecular Formula	C9H5F3O
Molecular Weight	186.13 g/mol
Synonyms	5-(Trifluoromethyl)benzofuran; 1-Benzofuran, 5-(trifluoromethyl)-; 5-Trifluoromethylbenzofuran; 5-CF3-Benzofuran; 5-(Trifluoromethyl)-1-benzofurane; 5-(Trifluoromethyl)benzo[b]furan
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1-Benzofuran is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.