Description

L-Allothreonine,2-Ethyl-,Methylester(9Ci) is a specialized, non-proteinogenic amino acid derivative with a defined stereochemistry. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, peptide mimetics, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and metabolic disease research.
• Peptidomimetics Research: Used to construct modified peptide backbones to enhance stability, bioavailability, and receptor selectivity of peptide-based drug candidates.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme mechanisms, protein-protein interactions, and cellular signaling pathways.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced, chiral herbicides or plant growth regulators.
• Academic & Contract Research: Serves as a reference standard and a reagent in university laboratories and CROs (Contract Research Organizations) for method development and discovery projects.

Basic Information

Product Name	L-Allothreonine,2-Ethyl-,Methylester(9Ci)
CAS No.	741219-01-2
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	L-2-Ethylallothreonine methyl ester; Methyl (2S,3S)-2-amino-2-ethyl-3-hydroxybutanoate; (2S,3S)-2-Amino-2-ethyl-3-hydroxybutyric acid methyl ester; L-2-Ethyl-threonine methyl ester (alloisomer); 741219-01-2; Amino acid derivative C7H15NO3
EINECS	Contact for details

Quality Control

Our production of L-Allothreonine,2-Ethyl-,Methylester(9Ci) adheres to stringent quality management protocols. Each batch is characterized and tested to ensure high chemical and stereochemical purity, with typical specifications meeting or exceeding research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and related substances is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (L-allo isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.