Description

1-[2-(Benzyloxy)-5-Bromophenyl]Adamantane is a high-purity, synthetically advanced organic intermediate characterized by its unique adamantane and brominated aromatic structure. This compound is of significant commercial value for its role in facilitating complex molecular transformations in pharmaceutical and advanced material research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs), particularly for candidates targeting central nervous system (CNS) disorders, due to the metabolic stability conferred by the adamantane moiety.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, where the bromophenyl group serves as a versatile site for further functionalization.
• Material Science Research: Serves as a precursor for organic semiconductors, liquid crystals, or metal-organic frameworks (MOFs), leveraging its rigid, three-dimensional structure.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global innovation market.

Basic Information

Product Name	1-[2-(Benzyloxy)-5-Bromophenyl]Adamantane
CAS No.	736992-49-7
Molecular Formula	C23H25BrO
Molecular Weight	397.35 g/mol
Synonyms	1-(5-Bromo-2-benzyloxyphenyl)adamantane; 1-[5-Bromo-2-(phenylmethoxy)phenyl]adamantane; Adamantane, 1-[5-bromo-2-(phenylmethoxy)phenyl]-; 5-Bromo-2-(1-adamantyl)phenyl benzyl ether; 1-(2-Benzyloxy-5-bromophenyl)adamantane
EINECS	Contact for details

Quality Control

Our 1-[2-(Benzyloxy)-5-Bromophenyl]Adamantane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.