Description

2-Ethoxycarbonylindole-5-Boronic Acid Pinacol Ester is a high-value, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used to create complex heterocyclic structures for developing new pesticides and herbicides with improved efficacy and selectivity.
• Material Science: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials, where the indole core contributes to optoelectronic properties.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes to study biological pathways and protein functions.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and for producing custom compounds in contract research organizations (CROs).

Basic Information

Product Name	2-Ethoxycarbonylindole-5-Boronic Acid Pinacol Ester
CAS No.	736990-02-6
Molecular Formula	C₁₇H₂₂BNO₄
Molecular Weight	315.18 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylate; 2-Carbethoxyindole-5-boronic acid pinacol ester; 1H-Indole-2-carboxylic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester; Ethyl 5-borono-1H-indole-2-carboxylate pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Ethoxycarbonylindole-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.