Description

2,1-Benzisothiazole-3-Propanenitrile,1,3-Dihydro-,2,2-Dioxide(9Ci) is a high-value, specialized heterocyclic organic compound with a unique sulfone and nitrile functionalized structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in sophisticated organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders or possessing specific enzyme inhibitory activity.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, or insecticides with unique modes of action.
• Organic Light-Emitting Diode (OLED) Materials: Acts as an electron-transport or host material component due to its rigid, conjugated benzisothiazole dioxide core.
• Ligand Synthesis in Catalysis: Serves as a starting point for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Polymer Modification: Incorporated as a functional monomer to impart specific thermal, optical, or solubility properties to advanced polymers.
• Academic & Industrial R&D: A valuable tool for chemical biology studies and exploring new reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	2,1-Benzisothiazole-3-Propanenitrile,1,3-Dihydro-,2,2-Dioxide(9Ci)
CAS No.	736178-12-4
Molecular Formula	C₁₀H₈N₂O₂S
Molecular Weight	220.25 g/mol
Synonyms	1,3-Dihydro-2,1-benzisothiazole-3-propanenitrile 2,2-dioxide; 3-(1,3-Dihydro-2,1-benzisothiazol-3-yl)propanenitrile 2,2-dioxide; 2,1-Benzisothiazol-3-ylpropanenitrile S,S-dioxide; 1,3-Dihydro-2,1-benzisothiazole-3-propionitrile 2,2-dioxide; Benzisothiazole propanenitrile dioxide derivative; (1,3-Dihydro-2,1-benzisothiazol-3-yl)acetonitrile S,S-dioxide (related structure).
EINECS	Contact for details

Quality Control

Our production of 2,1-Benzisothiazole-3-Propanenitrile,1,3-Dihydro-,2,2-Dioxide(9Ci) adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.