Description

cis-2-[2-(4-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its defined structure ensures precise biological activity and process reliability. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the fluorophenyl moiety for enhanced bioactivity.
• Organic Synthesis Research: Serves as a versatile chiral synthon in academic and industrial laboratories for constructing complex molecular architectures.
• API Development: Integral to the production route of specific Active Pharmaceutical Ingredients requiring a cis-configured cyclohexane carboxylic acid derivative.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in regulatory testing.

Basic Information

Product Name	cis-2-[2-(4-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid
CAS No.	736136-43-9
Molecular Formula	C15H17FO3
Molecular Weight	264.29 g/mol
Synonyms	2-[(4-Fluorobenzoyl)methyl]cyclohexanecarboxylic acid (cis-); cis-2-[(4-Fluorobenzoyl)methyl]cyclohexanecarboxylic acid; (1R,2S)-rel-2-[(4-Fluorobenzoyl)methyl]cyclohexanecarboxylic acid; 2-[(4-Fluorophenyl)(oxo)methyl]cyclohexane-1-carboxylic acid; 736136-43-9; cis-2-(2-(4-Fluorophenyl)-2-oxoethyl)cyclohexanecarboxylic acid; Cyclohexanecarboxylic acid, 2-[(4-fluorobenzoyl)methyl]-, cis-
EINECS	Contact for details

Quality Control

Our cis-2-[2-(4-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.