Description

trans-2-[2-(2-Methylphenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is a high-purity, synthetically derived carboxylic acid derivative featuring a unique structural motif. This compound serves as a versatile and valuable advanced pharmaceutical intermediate (API intermediate) and a key building block in organic synthesis. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the creation of novel active compounds. Its specific stereochemistry and functional groups make it critical for projects requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used as a precursor in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its complex cyclohexane and aryl ketone structure.
• Fine Chemical Production: Serves as a specialized building block for synthesizing complex molecules used in dyes, pigments, and performance materials.
• Organic Synthesis Research: Employed in academic and industrial R&D for methodological studies, including asymmetric synthesis, cyclization reactions, and carbon-carbon bond formation.
• Ligand and Catalyst Development: The carboxylic acid and ketone functionalities make it a candidate for developing novel chiral ligands or organocatalysts for stereoselective transformations.

Basic Information

Item	Details
Product Name	trans-2-[2-(2-Methylphenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid
CAS No.	735274-70-1
Molecular Formula	C₁₆H₂₀O₃
Molecular Weight	260.33 g/mol
Synonyms	2-[(2-Methylphenyl)(oxo)methyl]cyclohexane-1-carboxylic acid (trans-); (1R,2R)-2-[2-(2-Methylphenyl)-2-oxoethyl]cyclohexanecarboxylic acid; (1S,2S)-2-[2-(2-Methylphenyl)-2-oxoethyl]cyclohexanecarboxylic acid; trans-2-(2'-Methylphenacyl)cyclohexanecarboxylic Acid; 735274-70-1; α-(2-Methylbenzoyl)cyclohexaneacetic Acid (trans-); Cyclohexanecarboxylic acid, 2-[2-(2-methylphenyl)-2-oxoethyl]-, trans-
EINECS	Contact for details

Quality Control

Our trans-2-[2-(2-Methylphenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and consistent stereochemical integrity. Standard quality parameters include assay by HPLC, chiral purity determination, and control of specified impurities. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.