Description

cis-2-(4-Fluorobenzoyl)Cyclopentane-1-Carboxylic Acid is a high-purity, fluorinated cyclopentane carboxylic acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in its unique structural motif, which is essential for constructing complex molecules with specific stereochemistry and bioactivity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and other specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorobenzoyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including new cyclization and functionalization reactions.

Basic Information

Product Name	cis-2-(4-Fluorobenzoyl)Cyclopentane-1-Carboxylic Acid
CAS No.	733740-16-4
Molecular Formula	C13H13FO3
Molecular Weight	236.24 g/mol
Synonyms	2-[(4-Fluorophenyl)carbonyl]cyclopentane-1-carboxylic acid (cis-); (1S,2R)-2-(4-Fluorobenzoyl)cyclopentane-1-carboxylic acid; (1R,2S)-2-(4-Fluorobenzoyl)cyclopentane-1-carboxylic acid; cis-2-(p-Fluorobenzoyl)cyclopentanecarboxylic Acid; 4-Fluoro-α-oxo-benzenepropanoic acid cyclopentylidene derivative; Fluorobenzoyl Cyclopentanecarboxylic Acid; 733740-16-4; FCBCA
EINECS	Contact for details

Quality Control

Our cis-2-(4-Fluorobenzoyl)Cyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (cis-isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.