Description

3,5-Bis(Trifluoromethyl)Phenyldimethylchlorosilane is a high-value organosilicon reagent featuring a reactive chlorosilane group and a highly electron-withdrawing bis(trifluoromethyl)phenyl substituent. This unique structure makes it an essential building block for introducing lipophilic and sterically demanding silyl protecting groups or for creating advanced silicone polymers and functional materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for synthesizing novel compounds and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key reagent for introducing sterically hindered silyl protecting groups in complex molecule synthesis, particularly useful for sensitive or reactive functional groups.
• Agrochemical Synthesis: Used in the production of advanced active ingredients where the trifluoromethyl groups enhance biological activity and metabolic stability.
• Specialty Silicone Polymers: Serves as a monomer or cross-linking agent for synthesizing fluorinated silicone resins with unique surface properties, thermal stability, and chemical resistance.
• Surface Modification Agent: Employed to create hydrophobic and oleophobic coatings on glass, metals, and ceramics for advanced material applications.
• Ligand and Catalyst Precursor: Utilized in organometallic chemistry to develop novel ligands and catalysts for asymmetric synthesis and polymerization reactions.
• Electronic Materials: Potential use in the fabrication of organic semiconductors and dielectric materials due to its specific electronic properties.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Phenyldimethylchlorosilane
CAS No.	732306-23-9
Molecular Formula	C11H11ClF6Si
Molecular Weight	320.74 g/mol
Synonyms	Dimethyl[3,5-bis(trifluoromethyl)phenyl]chlorosilane; Chlorodimethyl[3,5-bis(trifluoromethyl)phenyl]silane; (3,5-Bis(trifluoromethyl)phenyl)dimethylchlorosilane; 3,5-Bis(trifluoromethyl)phenyldimethylsilyl chloride; Dimethyl(3,5-di(trifluoromethyl)phenyl)chlorosilane
EINECS	Contact for details

Quality Control

Our production of 3,5-Bis(Trifluoromethyl)Phenyldimethylchlorosilane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including GC, NMR, and Karl Fischer titration. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This compound is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and strong bases. Containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.