Description

(R)-Borocpg(+)-Pinanediol-Hcl CAS NO 732285-43-7 is a high-purity, chiral organoboron reagent, specifically the hydrochloride salt of a pinanediol-protected boronic ester derivative. This compound matters as a critical building block in asymmetric synthesis, enabling the precise introduction of chiral centers in complex molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry, process development, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Asymmetric Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds with high enantioselectivity.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of chiral drug candidates and APIs.
• Medicinal Chemistry & Drug Discovery: Enables the exploration of novel chemical space and structure-activity relationships (SAR) for new therapeutics.
• Process Chemistry Development: Serves as a reliable chiral synthon for scaling up synthetic routes under GMP conditions.
• Ligand and Catalyst Preparation: A precursor for synthesizing sophisticated chiral ligands and catalysts.
• Academic and Industrial Research: A valuable tool for methodology development in organic and organometallic chemistry.

Basic Information

Product Name	(R)-Borocpg(+)-Pinanediol-Hcl
CAS No.	732285-43-7
Molecular Formula	C₁₆H₂₈BClO₂
Molecular Weight	298.66 g/mol
Synonyms	(R)-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopentyl (1S,2R,3S,5R)-2,6,6-Trimethylbicyclo[3.1.1]heptan-3-yl Hydrogen Phosphate Hydrochloride; (1R,2S,5R)-2-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopentyloxy)-6,6-dimethylbicyclo[3.1.1]heptane Hydrochloride; (R)-Pinanediol Boronate Ester of Cyclopentylglycine Hydrochloride; (R)-Boronate-CPG Pinanediol Ester HCl; Boro-CPG(Pin) HCl
EINECS	Contact for details

Quality Control

Our (R)-Borocpg(+)-Pinanediol-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and elemental analysis, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.