Description

8-n-Boc-Amino-1,5-Dihydro-[1,2]Diazepino[4,5,6-Cd]Indol-6-One is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for the synthesis of novel drug candidates, particularly in oncology and neurological research, due to its role as a key building block for fused diazepinoindole scaffolds. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of targeted small-molecule therapies.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potent kinase inhibitors and other biologically active molecules.
• Oncology Research: Used in the discovery and development of novel anti-cancer agents targeting specific cellular pathways.
• Neurological Drug Development: Employed as a building block for compounds targeting central nervous system (CNS) disorders.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Supplied to CROs and CDMOs for route development and pilot-scale production of active pharmaceutical ingredients (APIs).
• Academic Research: Used in university laboratories for studying heterocyclic chemistry and novel synthetic methodologies.

Basic Information

Product Name	8-n-Boc-Amino-1,5-Dihydro-[1,2]Diazepino[4,5,6-Cd]Indol-6-One
CAS No.	731810-58-5
Molecular Formula	C₁₈H₂₀N₄O₃
Molecular Weight	340.38 g/mol
Synonyms	8-[(tert-Butoxycarbonyl)amino]-1,5-dihydro-[1,2]diazepino[4,5,6-cd]indol-6-one; 8-(Boc-amino)-1,5-dihydro-[1,2]diazepino[4,5,6-cd]indol-6-one; tert-Butyl N-(6-oxo-1,5-dihydro-[1,2]diazepino[4,5,6-cd]indol-8-yl)carbamate; Boc-protected diazepinoindolone; CAS 731810-58-5
EINECS	Contact for details

Quality Control

Every batch of 8-n-Boc-Amino-1,5-Dihydro-[1,2]Diazepino[4,5,6-Cd]Indol-6-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. Certificates of Analysis (COA) with full analytical data are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.