Description

5-Chloro-Hex-5-Enoic Acid is a versatile halogenated aliphatic carboxylic acid building block. This compound is valued for its bifunctional reactivity, featuring both a terminal chloroalkene group and a carboxylic acid moiety, enabling its use in various synthetic transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of more complex molecules, including potential active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Specialty Chemical Precursor: Serves as a starting material for producing fine chemicals, flavors, fragrances, and advanced polymer modifiers.
• Cross-Coupling Reactions: The chloroalkene functionality makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki).
• Derivatization Studies: Employed in academic and industrial R&D for creating libraries of derivatives via reactions at the acid group (amidation, esterification) or the alkene/chloride.
• Material Science Research: Investigated as a monomer or co-monomer for the development of functional polymers with specific properties.

Basic Information

Product Name	5-Chloro-Hex-5-Enoic Acid
CAS No.	731773-27-6
Molecular Formula	C6H9ClO2
Molecular Weight	148.59 g/mol
Synonyms	5-Chloro-5-hexenoic acid; 5-Chlorohex-5-enoic acid; 5-Hexenoic acid, 5-chloro-; 6-Chloro-5-hexenoic acid (tautomer); (5-Chloro-5-hexenoyl) acid; 5-Chloropent-4-ene-1-carboxylic acid; 4-Chloropent-4-enoic acid (isomer reference); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-Chloro-Hex-5-Enoic Acid is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay (by HPLC or GC), identity confirmation (by IR and/or NMR), and levels of key impurities. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.