Description

2-Chloro-3-(4-Fluorophenyl)-1-Propene is a versatile halogenated organic intermediate featuring a reactive allylic chloride moiety and a fluorinated aromatic ring. This unique structure makes it a valuable building block for synthesizing more complex molecules in advanced chemical research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl group.
• Liquid Crystal & OLED Material Research: Used in the synthesis of fluorinated organic compounds for electronic display and lighting applications.
• Cross-Coupling Reactions: The allylic chloride group participates in various palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) to form carbon-carbon bonds.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialty chemicals and complex organic molecules.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	2-Chloro-3-(4-Fluorophenyl)-1-Propene
CAS No.	731773-08-3
Molecular Formula	C9H8ClF
Molecular Weight	170.61 g/mol
Synonyms	1-(2-Chloroallyl)-4-fluorobenzene; 4-Fluorobenzyl Chloride Allyl Derivative; (4-Fluorophenyl)-2-chloropropene; 2-Chloro-1-(4-fluorophenyl)-2-propene; 3-(4-Fluorophenyl)-2-chloroprop-1-ene; 1-Chloro-2-(4-fluorophenyl)propene; Allyl 4-fluorobenzyl chloride; 731773-08-3
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(4-Fluorophenyl)-1-Propene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.