Description

5-(Tetrahydrofuran-2-Ylmethyl)-1,4,5,6-Tetrahydro-1,3,5-Triazine-2-Thiol is a specialized heterocyclic building block featuring a fused triazine-thiol structure with a tetrahydrofuranylmethyl substituent. This compound matters as a key intermediate for synthesizing complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, or plant growth regulators due to its bioactive triazine-thiol core.
• Ligand Synthesis: The thiol and heterocyclic nitrogen atoms make it a valuable starting material for creating chelating ligands in catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing specific chemical properties into specialty polymers.
• Chemical Biology Probes: Utilized in constructing molecular probes for studying enzyme inhibition or protein binding interactions.
• Material Science: Investigated for use in advanced electronic materials or as a corrosion inhibitor precursor due to its sulfur-containing moiety.

Basic Information

Product Name	5-(Tetrahydrofuran-2-Ylmethyl)-1,4,5,6-Tetrahydro-1,3,5-Triazine-2-Thiol
CAS No.	727664-33-7
Molecular Formula	C9H15N3OS
Molecular Weight	213.30 g/mol
Synonyms	5-[(Tetrahydrofuran-2-yl)methyl]-1,4,5,6-tetrahydro-1,3,5-triazine-2-thiol; 1,4,5,6-Tetrahydro-5-[(tetrahydro-2-furanyl)methyl]-1,3,5-triazine-2-thiol; 2-Mercapto-5-(tetrahydrofurfuryl)-1,4,5,6-tetrahydro-1,3,5-triazine; Tetrahydrofurfuryl-substituted triazinethiol; THF-Triazine-Thiol; 727664-33-7; 5-(Tetrahydrofuran-2-ylmethyl)-4,5,6,7-tetrahydro-1,3,5-triazine-2-thiol
EINECS	Contact for details

Quality Control

Our 5-(Tetrahydrofuran-2-Ylmethyl)-1,4,5,6-Tetrahydro-1,3,5-Triazine-2-Thiol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from HPLC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents and moisture. For optimal shelf life, minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.