Description

2-(4-Fluoro-Phenyl)-8-Methyl-Imidazo[1,2-A]-Pyridine-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its imidazopyridine core and aldehyde functional group. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as central nervous system (CNS) disorders and inflammation.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting GABA-A receptor modulation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its reactive aldehyde group.
• API Development: Serves as a building block for the development of new anxiolytic and sedative-hypnotic agents.
• Biochemical Tool Compound: Employed in pharmacological assays to study receptor interactions and biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.
• Academic Research: Used in university and institutional labs for exploratory research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	2-(4-Fluoro-Phenyl)-8-Methyl-Imidazo[1,2-A]-Pyridine-3-Carbaldehyde
CAS No.	727652-03-1
Molecular Formula	C15H11FN2O
Molecular Weight	254.26 g/mol
Synonyms	8-Methyl-2-(4-fluorophenyl)imidazo[1,2-a]pyridine-3-carboxaldehyde; 2-(4-Fluorophenyl)-8-methylimidazo[1,2-a]pyridine-3-carbaldehyde; Imidazo[1,2-a]pyridine-3-carboxaldehyde, 2-(4-fluorophenyl)-8-methyl-; 727652-03-1; 8-Methyl-2-(p-fluorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-Phenyl)-8-Methyl-Imidazo[1,2-A]-Pyridine-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, impurities, and full analytical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.