Description

1-(4-Formylphenyl)Piperidine-4-Carboxylic Acid is a high-purity organic building block featuring both a formyl and a carboxylic acid functional group on a piperidine scaffold. This compound is crucial for medicinal chemistry research and the synthesis of complex pharmaceutical intermediates. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets and receptor modulators.
• Ligand Synthesis: Used in the development of chelating agents and catalysts for asymmetric synthesis and metal-organic frameworks (MOFs).
• Peptidomimetic Chemistry: The carboxylic acid and aromatic aldehyde groups make it valuable for constructing constrained peptide analogs and macrocycles.
• Agrochemical Research: Employed in the design and development of new active ingredients for crop protection.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags, affinity probes, and other tools for biological target identification.
• Polymer Modification: Acts as a functional monomer or cross-linker for specialty polymers with tailored properties.

Basic Information

Product Name	1-(4-Formylphenyl)Piperidine-4-Carboxylic Acid
CAS No.	727396-60-3
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	4-Formyl-1-(4-formylphenyl)piperidine-4-carboxylic acid; 1-(4-Carboxyphenyl)piperidine-4-carboxaldehyde; 4-(4-Formylpiperidin-1-yl)benzoic acid; 1-(4-Formylphenyl)-4-piperidinecarboxylic acid; 4-(Piperidin-1-yl)benzaldehyde-4-carboxylic acid; 727396-60-3; 1-(4-Formylphenyl)piperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Formylphenyl)Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.